Aphorism 114 § 114 Aphorism 114 : With the exception of these narcotic substances, in experiments with moderate doses of medicine on healthy bodies, we observe only their primary action, i.e., those symptoms wherewith the medicine deranges the health of the human being and develops in him a morbid state…

Aphorism 113 § 113 Aphorism 113 : The only exceptions to this are the narcotic medicines. As they, in their primary action, take away sometimes the sensibility and sensation, sometimes the irritability, it frequently happens that in their secondary action, even from moderate experimental doses on healthy bodies, an increased…

Aphorism 112 § 112 Aphorism 112 : In those older prescriptions of the often dangerous effects of medicines ingested in excessively large doses we notice certain states that were produced, not at the commencement, but towards the termination of these sad events, and which were of an exactly opposite nature…

Aphorism 111 § 111 Aphorism 111 : The agreement of my observations on the pure effects of medicines with these older ones – although they were recorded without reference to any therapeutic object, – and the very concordance of these accounts with others of the same kind by different authors…

Aphorism 110 § 110 Aphorism 110 : I saw, moreover, that the morbid lesions which previous authors had observed to result from medicinal substances when taken into the stomach of healthy persons, either in large doses given by mistake or in order to produce death in themselves or others, or…

Aphorism 109 § 109 Aphorism 109 : I was the first that opened up this path, which I have pursued with a perseverance that could only arise and be kept up by a perfect conviction of the great truth, fraught with such blessings to humanity, that it is only by…

Aphorism 108 § 108 Aphorism 108 : There is, therefore, no other possible way in which the peculiar effects of medicines on the health of individuals can be accurately ascertained – there is no sure, no more natural way of accomplishing this object, than to administer the several medicines experimentally,…

Aphorism 107 § 107 Aphorism 107 : If, in order to ascertain this, medicines be given to sick persons only, ethough they even  administered singly and alone, then little or nothing precise is seen of their true effects, as those peculiar alterations of the health to be expected from the…

Aphorism 106 § 106 Aphorism 106 : The whole pathogenetic effect of the several medicines must be known; that is to say, all the morbid symptoms and alterations in the health that each of them is specially capable of developing in the healthy individual must first have been observed as…

Aphorism 105 § 105 Aphorism 105 : The second point of the business of a true physician related to acquiring a knowledge of the instruments intended for the cure of the natural diseases, investigating the pathogenetic power of the medicines, in order, when called on to cure, to be able…